I have started to experiment with wide area clustering of QuickPlace 7.0. In QuickPlace 8, it will use more Web 2.0 technologies and libraries such as Dojo. The impact of this will mean the QuickPlaces will become more chatty (more smaller and lighter requests). As a result, any latency issues might become more noticeable. To make the most of this, having your QuickPlace server as close as possible, will make the place much faster.
Once I can sort out any clustering issues, the next stage is to use directional dns from Neustar. This will direct the user to the closest server to the users location. For Australian users, this will be Sydney (latency of 20ms instead of the current 300ms), West Coast USA will be San Francisco (10ms instead of 80ms) and East Coast will keep hitting our main servers in Somerville, MA (10ms or less from New York). So far the Australian server is keeping up with the load and the West Coast should be online soon. I hope to have the world wide cluster working before LotusSphere 2007.